Mirvaso has set up the following web site:
Mirvaso is a new treatment released by Galderma in August/September 2013. Posts from users should be in this thread. It was announced in late February 2014 that Mirvaso is approved to be released in the EU. NICE has announced release in the UK is set for July 2014. MarketWatch reports on April 16, 2014 it is available in the UK. For more information on Mirvaso click here. If you have something you know about Mirvaso please post in this thread. It was announced in May 2014 that Galderma released this prescription in Canada as Onreltea (for a product description click here).
David Pascoe has an excellent breakdown explanation of the clinical trial results of the 330 trial users for the 29 days and the 276 trial users for the 365 days which shows excellent results.
As of November 2013, The price ranges from $266 to $274 for one tube (30 grams) at the different drugs stores in the USA. Source. David Pascoe has pointed out that in the UK Mirvaso may only cost £34 ($57) a tube which is quite a price difference! For more info click here.
Galderma is offering ways to save on Mirvaso if you click here.
Get the Mirvaso Mirror App
You should be aware that Mirvaso's active ingredient is bromonidine and that initial reports of using bromonidine for rosacea may produce rebound effects that you should be aware of.   It has been known from at least 2002 that brimonidine results in allergic reactions.  However, one report concluded the following:
"Once-daily topical BT gel 0.5% is not only efficacious at reducing facial erythema but also exhibits response within 30 minutes of application in a significant number of patients throughout both Phase III studies." 
For example, Mistica reports:
"I am a brimonidine victim. I ended up in the ER twice with the most horrific rebound flushing. I had nose bleeds, split lips and terrible flushing as the blood surged through my face looking for the weakest route. It would dart about, first engorging the side of my nose, then upper lip area, then the cheek, etc." 4th September 2013 12:04 AM Post #70 • Read a full report
Rebound vs Allergic Reaction - What's the Difference?
Scroll down to Post #6 and Post #9 in this thread to understand the difference between rebound and an allergic reaction. You are currently reading post #1 (see top right corner for post number).
According to Galderma, Mirvaso has had excellent results in clinical trials and you can read the results of those clinical trials in the prescription handout in pdf. You may read a conversation with the then current president of Galderma, Francois Fournier, about Mirvaso by clicking here. A few days later, the same magazine announced Fournier's ousting as president of Galderma. On December 9, 2013, the DHealthcare Daily reported in an article by Bradford Pearson, Layoffs Hit Fort Worth-based Pharma Company Galderma.
According to WebMD the top side effects of using Mirvaso are Redness of Skin and Temporary Redness of Face and Neck and classify this as 'less severe' and then list other sides effects as 'infrequent' or 'less severe.' Epocrates Online reports the following common reactions:
- burning sensation
- allergic contact dermatitis
A similar warning is also reported by Clinical Advisor. JAAD has published the first article on the rebound effect of Mirvaso by Routt and Levitt 
Galderma now has acknowledged that rebound is a concern with this post:
From initial reports from rosacea online groups and forums, there are few reports that Mirvaso is successful with rosacea sufferers. For example, hozer2K reports after reading posts at RF and other forums that he has found little successful posts using Mirvaso and a few have reported rebound effects. You should be aware that in a study done to know the incidence of allergy to brimonidine in patients treated for glaucoma that 25% of the patients were allergic to brimonidine.  However, Anna Holmes, Ph.D., explains, "Allergic sensitization was measured by patch testing patients across the Mirvaso clinical development program with suspected allergic contact dermatitis. The overall incidence of confirmed sensitization was less than 1%. Sensitization can occur, but the incidence is low." (See Post #7 below)
To report SUSPECTED ADVERSE REACTIONS, contact Galderma Laboratories, L.P. at 1-866-735-4137 or
FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
The following news blurbs from TV stations appear as legitimite news items but should be taken with the knowledge that they follow a pattern from a 'news feed' source that may be hired to promote Mirvaso. The pattern is for the news station to find a local doctor willing to appear on camera showing a willing patient who is being treated for Mirvaso. The report names the patient and the doctor and in each case the patient gives a positive report for Mirvaso. Since there is no follow through by the TV station on the patient, so we have no idea if after some time, say weeks or months later, if there are reports of rebound or if any of these patients later sing the Mirvaso Blues. For more information on how media news blurbs could be PR announcements masked as a news item, read this article by prwatch.org.
Here is the list:
(1) Ginger Royer's report shown on KPLC 7 News, Lake Charles, Louisiana, December 4, 2013: http://www.kplctv.co...&clipId=9597783
(2) Rosemary Stockinger's report shown on KDKA News, Pittsburg, PA, December 6, 2013: http://pittsburgh.cb...nt-for-rosacea/
Rosemary Stockinger is mentioned in a similar report shown on WCBS, New York on December 9, 2013: http://newyork.cbslo...sacea-patients/
Positive and Negative Anecdotal Reports
Please note about the following anecdotal reports in two spreadsheets (Positive and Negative):
Follow Up on Positive Reports
It is rarely possible to follow up on Positive Mirvaso anecdotal reports since most posters only post once and there is no way to follow up if the user has rebound issues later.
Scroll down down in this thread to Post #15 for a list of ambiguous anecdotal reports using Mirvaso.
Addendum on the above anecdotal reports
The above reports came from various online rosacea support groups, YouTube, WebMD, and other sites. The source of each report is shown in the last column of the spreadsheet.
This cute video explains Treato:
Another board to visit if you are interested is the Cafepharma Galderma thread on Mirvaso (posters apparently are professional reps of pharmaceutical companies):
There is a lot of non user comments about Mirvaso in the above threads and you have to search carefully to actually find a post by someone who actually has a prescription for Mirvaso who reports what they are experiencing, but I have done a search at this point in time for a significant number of hours and have confirmed what hozer2K reports that there are few reports confirming what Galderma is touting in their advertisements for Mirvaso. This may be because those users who accept a prescription for Mirvaso and it works for them simply do not report their success in online rosacea support groups and go their merry way happy as larks.
It takes a lot of time and searching to find actual user reports, and I will continue to work on this as I have time. I could use some help with this, but since I am basically the only person posting in this entire forum with the exception of the two guests (see posts #2, #3, and #4) that found a loophole, I simply don't have the time to browse all these posts. If I get time, I will resume the search. If you have the time, and can log into this forum, I would appreciate some help and simply post in this thread what you have found is your experience with Mirvaso or post links to those users who have reported their experience with Mirvaso. I could use some volunteer help with this thread. We do need volunteer forum moderators. The RRDi does indeed provide perks if you volunteer.
RRDi Members may post their experience with Mirvaso below in this thread. Guest_Julie_S is the first guest to actually report her experience which is in this thread as Post #2 and #3. Another guest posted #4 who reports Mirvaso is wonderful. However, if you read Post #5 which I also posted, it explains that Posts #2 & 3 and Post #4 are created by guests who were able to post until I closed the gate. Only RRDi members can post now. And the problem with RRDi members is that they do not post in our forum. I don't know why? I sent an email to all the members asking them to post and what we can do to make it easier to post. No replies.
You may wonder why the RRDi doesn't usually allow guest posts of anonymous posters. Now we do. But the RRDi Member Forum requires your contact information and has over 800 members. However these members simply do not post here, for whatever reason. I have sent out a newsletter asking specifically what can we do to make the RRDi forum easier to post and received no solutions on what we can do to stimulate RRDi Members to post here. The other problem is that of the 800+ members, some opt out of the newsletter, and I get a huge number of bounce back messages since everyone changes their email addresses just as they do cell phone numbers, which makes it even more difficult to send the newsletter since I received a notice from our host that if we send another newsletter with as many bounce back messages as the last one, they will shut us down. It is a huge undertaking to weed out the members who do not have valid email addresses, and I did do this volunteer work. If anyone wants to volunteer to help me with moderating this forum, please contact me. In 2014 the RRDi has set up a Guest Forum where anyone can post anonymously. If you want to post anonymously in this RRDi Guest Forum all you do is use a display name that doesn't reveal your real name, which is what they do at other rosacea forums.
One odd item is that those who post positive Mirvaso experiences usually post once and then we never hear from them again. So there is no way to follow up on these positive reports to see if these users experience rebound issues later since we usually never hear from them again.
Ethan T. Routt, BA Jacob O. Levitt, MD
J Am Acad Dermatol. 2014 Feb;70(2):e37-8. doi: 10.1016/j.jaad.2013.10.054.
 J Am Acad Dermatol. 2014 May;70(5):e109-10. doi: 10.1016/j.jaad.2014.01.853.
 Can J Ophthalmol. 2002 Feb;37(1):21-6.
Department of Ophthalmology, Université de Sherbrooke, Que.
 J Drugs Dermatol. 2014 Jun 1;13(6):699-704.Improvement in facial erythema within 30 minutes of initial application of brimonidine tartrate in patients with rosacea.